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Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA)

Special Issue on Fluorine-19 Magnetic Resonance: Technical Solutions, Research Promises and Frontier Applications


The potential applications of Fluorine-19 Magnetic Resonance (19F MR) have long been recognized, but have only recently come to the forefront of preclinical and clinical research. 19F MR spans across many fields, from the chemistry of label synthesis and production, through to biological applications and into image acquisition and processing. Clinical research in this area is also rapidly expanding, as evidenced by recently approved studies using 19F MR for cell tracking in patients. Background-free imaging and quantification are amongst the strengths of 19F MR methods, although challenges pertaining to signal sensitivity and cell detection limits exist. Efforts to develop 19F MR technologies in order to realize their potential are also fueled by the ever increasing quest of advancing the applications of biomedical and diagnostic MRI. The field of 19F MR has matured and evolved at a tremendous pace in the last few years. The ever-increasing number of publications and abstracts at conferences is a testament for this. The enthusiasm and overwhelming number of participants at the 2nd symposium on 19F MR (http://bit.ly/redhotmri) in October 2017 led to the decision to set up a special issue on the topic in a first class, internationally reputed journal that publishes on multidisciplinary MR research. Magnetic Resonance Materials in Physics, Biology and Medicine (MAGMA) covers all aspects around advances in MR techniques as well as application in medicine and biology.

MAGMA will publish a special issue on Fluorine-19 Magnetic Resonance in the first volume of 2019. Articles will be available online after acceptance. This special issue will cover a broad array of topics, ranging from the development of 19F imaging contrast agents to in vivo 19F MR applications. It is meant to provide an overview of the state-of-the-art of 19F MR, to discuss clinical relevance and to explore new concepts, emerging applications and future directions. The special issue aims to highlight 19F MR methodologies, including those that increase MR sensitivity for novel application, in animal and human studies. Topics for research papers include, but are not limited to:
•    novel contrast agents
•    MR hardware and RF technology
•    pulse sequence methods
•    post-processing techniques
•    19F MR in studies of animal disease models
•    19F MR in clinical trials
•    application of high and ultrahigh field 19F MR in human studies

This special issue will offer a unique space for new concepts and preliminary applications, to continue to motivate new research in the field.

The goal is to bridge disciplinary boundaries, and inspire the community to invest time and energy into solving the remaining technical problems, and expanding the reach of 19F MR into new territory, with the ultimate aim of addressing unmet clinical needs. This will require the coordinated efforts of basic scientists in the fields of MR physics, biomedical engineering, neuroscience and physiology, and translational collaborations with clinicians in radiology, neurology, cardiology, oncology, nephrology, and other related specialties.

In order to meet the time line, papers should be submitted as soon as possible, and not later than 1st July 2018. Papers should be submitted through the normal submission procedures on the web (http://www.editorialmanager.com/mrmp ). Authors should indicate in their cover letter that the manuscript is submitted "For inclusion in the Special Issue on Fluorine-19 Magnetic Resonance”.

The special issues of MAGMA reach a wide audience, and are highly cited. This special issue on fluorine-19 MR is an excellent opportunity to showcase your work in a high profile format. We look forward to receiving your manuscripts.

David G. Norris                       
Editor                     

Mangala Srinivas
Ulrich Flögel
Sonia Waiczies
Philipp Boehm-Sturm
Thoralf Niendorf
Guest editors

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