School of MRI > Courses 2017 > Body Diffusion-Weighted Imaging: Solving Clinical Problems and Diagnostic Dilemmas
Body Diffusion-Weighted Imaging: Solving Clinical Problems and Diagnostic Dilemmas

November 8-10, 2017

Course organiser:
Dow-Mu Koh


Local organiser:
Maria Antonietta Bali, Brussels/BE
Pietro Scillia, Brussels/BE

Course venue:
Musée de la Medicine
Campus Erasme – Place Facultaire
Route de Lennik 808
1070 Anderlecht, Brussels

M. A. Bali, M. Blackledge, H. Chandarana, F. De Keyzer, L. Fournier-Dujardin, N. Grenier, D.-M. Koh, C. Matos, A. Padhani, I. Thomassin-Naggara


Please click here to download the programme of the course.

Course duration:

Wednesday - Friday

The aim of this course:
Diffusion-weighted MR imaging is now widely used in the body to improve patient management. In this newly revised course, we will emphasize on the practical aspects of using diffuson-weighted MRI to solve common clinical problems and diagnostic dilemmas in the body. We will review both the basic and advanced theories of body diffuson-weighted MRI, as well as the implementation of imaging protocols at 1.5T and 3.0T, including whole body imaging. The growing use of diffusion-weighted MRI for evaluating disease heterogeneity will be discussed, as well as the complimentary role of the technique on a hybrid MR-PET imaging system.

Participation requirements:

Participants should be physicians or MR radiographers/technicians who have basic knowledge in MRI techniques and are experienced in MRI (6 months minimum).

Learning Objectives

DWI: Principles, Theory, Nomenclature and beyond ADC

•Principles of DW-MRI
•Diffusion-weightings: b-values
•Monoexponential ADC quantification
•Non-monoexponential diffusion models: IVIM, Stretched exponential, diffusion kurtosis imaging
•Measurement repeatability of DWI quantification

Getting the Best Body DWI at 1.5T and 3.0T: A Practical Approach
•Imaging sequences for body imaging
•Technical implementation at 1.5T and 3.0T
•Pros and Cons of DWI at 1.5T and 3.0T
•Strategies to improve image signal-to-noise and reduce artefacts for DWI

Problem Solving in the Liver and Upper Abdomen
•Clinical protocols of DWI in the liver and upper abdomen
•Evaluation of focal lesions in the cirrhotic and non-cirrhotic liver
•Applications in the small bowel and colon
•The value of DWI for tumour detection, disease characterization and assessment of treatment response

What Is the Role of DWI for Pancreatic and Biliary Diseases?

•Technical implementation of DWI for evaluating the pancreas and biliary tree
•Combining DWI with conventional MRI for disease detection and characterization
•Advanced DWI models for pancreatic diseases
•Assessing treatment response using DWI
•Diagnostic pitfalls

Renal Pathologies: The Added Value of DWI
•Clinical implementation of DWI in the kidneys and upper urinary tract
•Clinical applications of DWI for diffuse renal disease and assessment of renal function
•The application of DWI for the assessment of focal renal lesions
•Advanced DWI models for evaluating the kidneys

Improving the Assessment of the Uterus and Adnexal Masses
•Technical implementation for evaluating the female pelvis
•DWI evaluation of the uterus and adnexal masses
•Application of DWI for tumour detection, disease characterization and the assessment of treatment response
•Potential diagnostic pitfalls

Peritoneal Disease: Improving Detection and Patient Management
•Current limitations of peritoneal disease assessment using CT and PET imaging
•Impact of peritoneal disease in cancer management
•Role of DWI for detecting peritoneal disease, evaluation for debulking surgery and assessing treatment response in ovarian cancer
•Unmet challenges

Assessing and Directing Treatment of Bone Disease
•Current challenges of evaluating metastatic bone disease and diffuse marrow involvement
•Implementation of whole body DWI to assess marrow disease
•Image interpretation (including MET-RADS-P reporting system)
•Understanding bone marrow ADC and fat fraction quantification
•Avoidance of pitfalls

Tumour Heterogeneity in the Era of Targeted Treatments: What Can MRI and DWI Tell us?
•Understand tumour heterogeneity as a major challenges in oncology
•Techniques to describe inter-tumour and intra-tumour heterogeneity
•Applying MRI and DWI to demonstrate tumour heterogeneity linked to tumour biology
•The role of radiomics in assessing tumour heterogeneity

Advanced DWI Methods and Use with Other Quantitative and Hybrid Imaging Technologies
•Understand the emerging use of advanced DWI methods in oncology
•The role of multiparametric MRI for the disease assessment (including prostate cancer as example)
•Combining DWI with hybrid Imaging (including PET-MRI) as potential one-stop-shop for cancer assessment
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