School of MRI > Courses 2018 > Clinical fMRI & dMRI - Theory and Practice
Clinical fMRI & dMRI - Theory and Practice

June 28-30, 2018

Course organiser:
Alexander Leemans

Local organiser:
Derek Jones, Cardiff/UK

Course Venue:
University of Cardiff Brain Research Imaging Centre
School of Psychology
Maindy Road
CF24 4HQ
United Kingdom

V. Giampietro, C. J. Hodgetts D.K. Jones S, A. Leemans, S. Lehéricy, R. Peeters, S. Rombouts, M. Smits, C. Tax, S. Williams 

Please click here to download the programme of the course.

Course duration:
Thursday morning – Saturday noon

The aim of this course:
The aim of this course is to convey in-depth knowledge about functional MR imaging (fMRI) and diffusion (tensor & beyond) MR imaging (dMRI), with a focus on clinical practice. These advanced MR neuroimaging techniques are increasingly applied to the study of the healthy and diseased human brain and provide information about the brain’s activity and its connections. The course will offer an overview of present methodologies, an update about functional anatomy and an
overview of clinical as well as some research applications. These topics are taught using a mixture of lectures and
small group exercises. In addition, a practical session on a 3T MR system performing fMRI studies in healthy volunteers
complements the taught elements of the course. Finally, special attention is given to the (clinical) interpretation of
specific cases, including results from both routine presurgical fMRI examinations and more advanced fMRI (group) studies.
We are happy to welcome you to this course in Cardiff!

Participation requirements:

Physicians and technicians/radiographers with good knowledge of MR techniques; minimum of 3 months’ experience in applied MR imaging and/or fMRI or dMRI.

Learning Objectives

Basics of fMRI

  • Physiological principles of fMRI
  • Blood oxygen level dependent contrast (BOLD) MR technique and imaging sequences
  • Resting state fMRI

Basics of dMRI

  • Physical principles of anisotropic diffusion
  • dMRI technique and imaging sequences
  • Concepts of quantification of white matter microstructure
  • Concepts of fibre tractography

Experimental and Paradigm Design
  • Technical set-up for fMRI
  • Categorical, factorial, parametric designs
  • Blocked versus event-related paradigms
  • Paradigms: development, implementation and pitfalls

Data Analysis
  • Spatial preprocessing
  • Statistical analysis
  • Fibre tractography

Functional Anatomy
  • Motor system
  • Language system
  • Visual system
  • Auditory system
  • Applications and (clinical) interpretation

Presurgical fMRI/dMRI
  • Risk estimation in brain tumour patients
  • Combining fMRI and dMRI in brain tumour patients
  • Challenges and pitfalls

fMRI/dMRI in Psychiatry
  • Applications in psychiatric disease
  • Pharmacological fMRI
  • Pitfalls
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