The aim of this course is to convey in-depth knowledge about functional MR imaging (fMRI) with a focus on clinical practice. This advanced MR neuroimaging technique is increasingly applied to the assessment of the healthy and diseased human brain and provides information about the brain’s activity. The course will offer an overview of present methodologies, functional neuroanatomy, and clinical as well as some research applications. These topics are taught using a mixture of lectures, practical data analysis sessions, and small group case discussions. Special attention is given to the interpretation of clinical cases, including results from both task-based presurgical fMRI examinations and more advanced resting-state fMRI studies.